
Appearance
''Sistrurus miliarius'' is a small species with adults usually growing to 40–60 cm in total length. The maximum reported total length is 78.8 cm.At midbody, the rows of dorsal scales usually number 23. The dorsal pattern consists of a series of oval or subcircular spots with reasonably regular edges. The spots on the flanks are mostly round and not much higher than they are wide.
Belly pigmentation towards the rear is more limited to indistinct blotches found on pairs of adjacent scales. Juveniles have a color pattern that is similar to the adults, although it may be paler or more vividly marked, and the tip of the tail is yellow.

Naming
Common names for ''S. miliarius'' include pygmy rattlesnake, ground rattlesnake, hog-nosed rattlesnake, little rattlesnake, miliar rattlesnake, North American smaller rattlesnake, oak-leaf rattler, pygmy ground rattlesnake, small rattlesnake, southeastern ground rattlesnake, southern ground rattlesnake, southern pygmy rattlesnake, spotted rattler, spotted rattlesnake, southern rattlesnake.Status
This species is classified as least concern on the IUCN Red List of Threatened Species. Species are listed as such due to their wide distribution, presumed large population, or because it is unlikely to be declining fast enough to qualify for listing in a more threatened category. The population trend is stable. It was assessed in 2007.Behavior
''Sistrurus miliarius'' is usually seen in the summer sunning itself or crossing the road late in the day. The tiny rattle makes a buzzing sound that can only be heard from a few feet away. Some individuals are very aggressive and strike furiously, while others seem lethargic and do not even attempt to rattle. It does not dig its own burrows, but rather uses those dug by small rodents or gopher tortoises.Habitat
''Sistrurus miliarius'' reportedly inhabits flatwoods, sandhills, mixed forests, and floodplains, and is also found near lakes and marshes.Food
The diet of ''S. miliarius'' includes small mammals and birds, lizards, insects, and frogs, as well as other snakes. Pygmy rattlesnakes also include giant desert centipedes in their diet, which they hunt by active pursuit, grabbing and flipping the centipedes around while simultaneously injecting venom to prevent injury by the victim. They also ambush lizards such as skinks by using their tails as lures, as is common in many other species of vipers.Defense
Since ''S. miliarius'' is unable to produce much venom, it is unlikely to be able to deliver a fatal bite to a human adult. Brimley wrote that although it was too small to be really dangerous, its bite "will give the victim quite an unpleasant time for several days." However, bites involving children have resulted in prolonged hospitalization, with reports of necrosis.This snake produces cytotoxic venom that is strongly hemorrhagic and tissue toxic, but devoid of any neurotoxins. The venom was the basis for the development of the drug eptifibatide, which is used to prevent clotting during a heart attack. The venom is somewhat different in that it contains substantial amounts of serotonin and related tryptamine compounds. Antivenin does not appear to be effective in the treatment of bites of ''S. miliarius'', although CroFab does seem to do a better job than ACP, at least in some animal models.
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