Appearance
It can be differentiated from similar skullcaps like Scutellaria ovata, Scutellaria incana, and Scutellaria serrata by leaf structure, the presence of glandular hairs (on stems, stalks, and calyces), flower size, and pubescence.References:
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http://www.illinoiswildflowers.info/woodland/plants/hry_skullcap.html